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For questions,
comments or suggestions about this web site, please contact
Gwen Dressing
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 Yefei Pang, Ph.D.
Post-Doctoral Fellow
The University of Texas at Austin
Marine
Science Institute
750 Channelview Drive, Port Aransas, TX 78373-5015
Phone: (361) 749-6788; Fax: (361) 749-6777
E-mail: yfpang@utmsi.utexas.edu
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CURRENT RESEARCH
In addition to classical genomic actions,
both progestins and estrogens also exert rapid nongenomic actions
initiated at the cell surface in reproductive tissues, presumably by
binding to membrane localized receptors. Recently, our lab has cloned and
analyzed membrane progestin receptors in the spotted seatrout and humans.
A G protein coupled membrane estrogen receptor, GPR30, has also been
characterized in human breast cancer cells by our team. My research is
focused on further characterization of membrane progestin and estrogen
receptors in human and fish models. I am currently studying the molecular
structures of these genes and proteins as well as their G-protein coupling
signal transduction pathways.
EDUCATION
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Ph.D. Degree: Department of
Biology, Chinese University of Hong Kong, 2001
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M.S. Department of
Biology, Inner Mongolia University, China,1989
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B.S. Department of Biology,
Inner Mongolia University, China, 1982
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TRAINING
| 1992- 1998 Assistant Professor, Head of Lab Animal center,
Laboratory Animal Science Center, Medical College of Shantou University,
China. Teaching: Technology in Medical Lab Animal for
postgraduate student. Research: Genetic variation and analysis of
hamster, In vitro fertilization and culture of mouse oocytes. |
| 1989-1992 Lecture and Researcher, The Research Center for Lab
Animals Inner Mongolia University, China Teaching: The Technology
of Reproductive Biology, Genetics, Guidance of graduate research for
undergraduate students. Research: Fertilization and development
of mammal oocyte In vitro, Embryo culture, Micromanipulation (splitting,
nuclear transfer etc.) and frozen storage of pre-implantation embryos.
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| 1982-1986, Teaching assistant, Department of Biology Inner Mongolia
Medical college, China Teaching: Medical Biology, Fundamental Zoology,
Human Genetics and Cell Biology Research: The variation and
analysis of human chromosomes. |
CONFERENCES
| 35th Annual meeting of the Society for the Study of Reproduction,
July 28-31, Baltimore, Maryland USA Effects of in vitro treatment with
estradiol-17β and gonadotropin on membrane estrogen receptor
concentrations in Atlantic croaker testis. |
| 4th International symposium on fish Endocrinology, July 31-August 3,
2000, Seattle, Washington, USA. Poster titles:
| 1. Gonadotropin and activin enhance maturational competence of the
oocytes in the zebrafish, Danio rerio. |
| 2. Gonadotropin stimulation of activin βA and activin type II
receptor expression in the ovarian follicular cells of the zebrafish,
Danio rerio. |
| 3. Epidermal growth factor (EGF) and transforming growth factor-α
(TGF-α) promote oocyte maturation in the zebrafish, Danio rerio:
potential role of the ovarian activin regulatory system. |
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| ARTA (Assisted Reproductive Technology/Andrology) Twin Conferences:
August 18-20, Tossa de Mar, Spain / August 22-23, 1992, Munich, Germany
Oral presentation title: Development and freezing of bovine embryos
derived from IVF. |
| International Symposium of Biotechnology on Animal Reproduction,
July 31-August 3, 1992, Urumuqi, China Poster title: Nuclear
transplantation in the bovine embryos derived from IVM and IVF. |
| Beijing International Symposium on Reproductive Biology, October
23-26,1990, Beijing, China Plenary lecture: In vitro development of
bovine oocytes matured and fertilized in vitro and calving after embryo
transfer. |
PUBLICATIONS
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Thomas P,
Dressing G,
Pang Y,
Berg H,
Tubbs C,
Benninghoff A,
Doughty K.
Progestin, estrogen and androgen G-protein coupled receptors in fish
gonads.
Steroids.
2005 Nov 11; [Epub ahead of print] |
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Thomas P, Pang Y,
Filardo EJ, Dong J. Identity of an estrogen membrane
receptor coupled to a G protein in human breast cancer cells.
Endocrinology. 2005 Feb;146(2):624-32. |
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Thomas P, Pang Y, Zhu
Y, Detweiler C, Doughty K. Multiple rapid progestin
actions and progestin membrane receptor subtypes in fish.
Steroids. 2004 Aug;69(8-9):567-73. |
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Zhu Y, Rice CD, Pang
Y, Pace M, Thomas P. Cloning, expression, and
characterization of a membrane progestin receptor and evidence it is an
intermediary in meiotic maturation of fish oocytes. Proc Natl Acad Sci U
S A. 2003 Mar 4;100(5):2231-6. |
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Yefei Pang and Wei Ge, Epidermal growth
factor and TGFalpha promote zebrafish oocyte maturation in vitro:
potential role of the ovarian activin regulatory system. Endocrinology.
2002 Jan;143(1):47-54. |
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Yefei Pang and Wei Ge, Gonadotropin and
activin enhance maturational competence of oocytes in the zebrafish (Danio
rerio). Biol Reprod. 2002 Feb;66(2):259-65.
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Yefei Pang and Wei Ge, Gonadotropin
regulation of activin betaA and activin type IIA receptor expression in
the ovarian follicle cells of the zebrafish, Danio rerio. Mol Cell
Endocrinol. 2002 Feb 25;188(1-2):195-205.
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Yefei Pang and Wei Ge, Activin stimulation
of zebrafish oocyte maturation in vitro and its potential role in
mediating gonadotropin-induced oocyte maturation. Biol Reprod 1999, 61:987
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Yefei
Pang et al., The study for the mechanisms of developmental block of KM
strain mouse embryos derived from IVF. Chi J Cell Biol 1996, 18:41 (in
Chinese with English abstract)
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Yefei Pang et al., The observation study
on the tissue structure of reproductive glands in the albino golden
hamster. Bulletin Shantou Univ Med Coll 1996, 1:17 (in Chinese with
English abstract)
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Yefei Pang et al., Study on the in vitro
fertilization and culture system of KM strain mouse oosytes, Bulletin
Shantou Univ Med Coll 1995, 1:20 (in Chinese with English abstract)
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Yefei Pang et al., Preliminary study on
the in vitro fertilization of domestic camel (Camelus bactrianas). Chi J
Zool 1993, 28(6):35 (in Chinese with English abstract)
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Yefei Pang et al., The study on the
culture conditions of in vitro fertilized bovine embryos. Acta Sci Natu
Univ Intramogol 1992, 23:424 (in Chinese with English abstract)
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B Shorgan and Yefei Pang, Development of
freezing of bovine embryos derived from IVF. Assi Reprod Technol Androl
1992, 3:97
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Yefei Pang et al., The effects of
cryoprotectants and plunging temperature on the freezing embryos of KM
strain mouse. Chi J Lab Anim Sci 1991 (in Chinese with English abstract)
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